Antibody-dependent enhancement
NON-NEUTRALIZING ANTIVIRAL PROTEINS FACILITATE VIRUS ENTRY INTO HOST CELLS, LEADING TO INCREASED INFECTIVITY IN THE CELLS
Antibody dependent enhancement; Enhancing antibody; Immune enhancement; Disease enhancement; Vaccine-enhanced infection
Antibody-dependent enhancement (ADE), sometimes less precisely called immune enhancement or disease enhancement, is a phenomenon in which binding of a virus to suboptimal antibodies enhances its entry into host cells, followed by its replication. The suboptimal antibodies can result from natural infection or from vaccination.